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Clinical Trials/NCT03198403
NCT03198403
Completed
Phase 4

The Effect of Popliteal Plexus Block on Postoperative Pain After Total Knee Arthroplasty

Regionshospitalet Silkeborg1 site in 1 country17 target enrollmentAugust 1, 2017

Overview

Phase
Phase 4
Intervention
Bupivacaine-epinephrine
Conditions
Popliteal Plexus Block
Sponsor
Regionshospitalet Silkeborg
Enrollment
17
Locations
1
Primary Endpoint
The percentage of patients with postoperative pain NRS
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

The study aims to investigate the effect of the Popliteal plexus block (PPB) on postoperative pain after total knee arthroplasty

Detailed Description

Cadaver dissection studies have shown a spread of dye to the popliteal fossa and colored the popliteal plexus by injecting in the distal part of the adductor Canal. The popliteal plexus is formed by contribution from the tibial and the obturator nerves. Investigators hypothesized that a PPB may reduce postoperative pain after total knee arthroplasty.

Registry
clinicaltrials.gov
Start Date
August 1, 2017
End Date
September 28, 2017
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Charlotte Runge

Consultant anesthetist, Principal investigator

Regionshospitalet Silkeborg

Eligibility Criteria

Inclusion Criteria

  • patients undergoing total knee arthroplasty in spinal anesthesia
  • age \> or = 18 years
  • American Society of Anesthesiologists (ASA) status I-III
  • Informed consent

Exclusion Criteria

  • Patients unable to cooperate
  • Patients not able to speak Danish
  • Pregnancy
  • Contraindication towards ana Medical product used in the study
  • Preoperatively reduced sensation on the medial and lateral part of the lower leg
  • Patients with diabetic requiring Medical treatment
  • Preoperative daily intake of opioids

Arms & Interventions

Popliteal plexus block

Patients with an FTB, reporting postoperative pain (NRS \> 3) will have a popliteal plexus block

Intervention: Bupivacaine-epinephrine

Outcomes

Primary Outcomes

The percentage of patients with postoperative pain NRS

Time Frame: 0 - 60 minutes

Evaluated as the percentage of patients with postoperative pain NRS \>3, dropping in pain score to NRS = or \< 3 after the PPB

Secondary Outcomes

  • Percentage of patients having a femoral triangle block(FTB) reporting NRS > 3(Pain scores every 15 minutes (from end injection FTB to NRS>3 or 3 hours after full sensation of the leg))
  • Turn off time of spinal anesthesia(Time from arrival in PACU and during maximum 6 hours)
  • The effect of the PPB on cutaneous sensation(NRS every 5 minutes after PPB (From 0 - 60 minutes after PPB))
  • The effect of the PPB on muscle strength of the foot(Baseline and 1 hour after PPB)
  • Onset time of PPB(NRS every 5 minutes after PPB (From 0 - 60 minutes after PPB))
  • Correlation between normal cutaneous sensation and developing of pain(From arrival in PACU and during maximum 6 hours)

Study Sites (1)

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