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Clinical Trials/NCT03590587
NCT03590587
Unknown
Not Applicable

Rapid Structural and Functional Improvements in Following 0.19 mg Fluocinolone Acetonide (FAc) Implant in Diabetic Macular Edema Patients With Poor Visual Acuity: 12-month Audit Results From United Arab Emirates

Benha University1 site in 1 country30 target enrollmentStarted: January 13, 2017Last updated:

Overview

Phase
Not Applicable
Enrollment
30
Locations
1
Primary Endpoint
BCVA

Overview

Brief Summary

The Health Authority - Abu Dhabi (HAAD) approved the reimbursement of the slow release FAc implant (ILUVIEN) and it is now available for the treatment of diabetic macular edema (DME) in persons who have been previously treated with a course of corticosteroids and did not have a clinically significant rise in intraocular pressure. We performed a retrospective 12-month audit to assess the efficacy and safety of the FAc implant in our clinical practice.

Detailed Description

Twenty patients with pseudophakic lenses, treated with ILUVIEN, were investigated to evaluate functional and anatomical characteristics and outcomes (visual acuity [VA; ETDRS letters score], central macular thickness [CMT] and intraocular pressure [IOP]) at baseline, weeks 2-4 and months 3, 6 and 12 months.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Retrospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Pseudophakic

Exclusion Criteria

  • Other causes of macular edema.
  • Know case of gaucoma

Arms & Interventions

1

patients treated with 0.19 mg fluocinolone acetonide (FAc) implant for 12 months

Intervention: 0.19 mg fluocinolone acetonide (FAc) implant (Device)

Outcomes

Primary Outcomes

BCVA

Time Frame: 12 months

best corrected visual acuity

Secondary Outcomes

  • CMT(12 months)
  • IOP(12 months)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Ahmed Elbarky

assistant professor of ophthalmologyu

Benha University

Study Sites (1)

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