跳至主要内容
临床试验/NCT04749082
NCT04749082Unknown不适用

Long Term Follow up of Patients With Thoracolumbar Spondylodiscitis Treated Surgically by Posterior Approach in Assiut University Hospitals

Assiut University0 个研究点目标入组 40 人开始时间: 2021年1月31日最近更新:
适应症

试验速览

阶段
不适用
入组人数
40
主要终点
Bony fusion success

研究概览

简要总结

To evaluate the long term outcomes of patients with thoracolumbar spondylodiscitis treated surgically by posterior approach.

Outcomes include bony fusion, neurological improvement, pain improvement, implant related complication, recurrence of infection and or reoperation rate

详细描述

spondylodiscitis is characterized by infection that primarily affects the intervertebral disc and adjacent vertebrae. The estimated incidence of spondylodiscitis, ranging from 0.2 to 10 per 100,000 inhabitants per year, has increased in recent years, which is likely associated with an aging population, higher prevalence of chronic disease, and more effective diagnostic techniques. Spondylodiscitis is a life-threatening disease with a mortality rate of 2-20% that is often associated with potential complications, such as paraspinal abscess, epidural abscess, meningitis, spinal instability, and neurologic deficiency. The relapse rates were reported to be as high as 32% in the literature. The aims of this study are to evaluate improvements, complications, recurrence and reoperation rates in Assiut university hospitals.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

年龄范围
20 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • • All patients had thoracolumbar spondylodiscitis from number 1 thoracic vertebra till number 1 sacral vertebra.
  • Treated surgically by posterior approach only.

排除标准

  • • Patients with incomplete follow up.
  • Multifocal discitis.

结局指标

主要结局

Bony fusion success

时间窗: 2 years

the degree of bridging bone across the fused vertebral bodies by using x-ray, CT scan and MRI if needed

次要结局

  • modified Oswestry disability index(2 years)
  • visual analogue scale(2years)
  • American spinal injury Association (ASIA) Impairment score(2 years)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Micheal Bassem Elia

Principal investigator

Assiut University

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