MedPath

Development Of a Virtual Stress Inoculation Training (SIT) Platform and Mobile Health App

Not Applicable
Recruiting
Conditions
PTSD
Trauma and Stressor Related Disorders
Traumatic Brain Injury
Interventions
Behavioral: SIT NAVIGATOR
Behavioral: Stress NAVIGATOR (Mobile Health Application)
Registration Number
NCT06494319
Lead Sponsor
The University of Texas Health Science Center, Houston
Brief Summary

The purpose of this study is to demonstrate the feasibility and utility of SIT delivered asynchronously (self-paced) via fully virtual platform with and without the aid of a mobile health application and to determine initial change over baseline in terms of reduction in PTSD symptoms and improvement in resiliency in participants receiving the virtual SIT prototype, using Linear Mixed Models (LMMs),

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
20
Inclusion Criteria
  • US Military Veterans / Service Members
  • diagnosis of PTSD as measured by a Posttraumatic Symptom Checklist for DSM-5 (PCL-5) score of >33
  • history of combat trauma and/or military service in an imminent danger pay area
  • be fluent in English.
  • be capable of giving signed informed consent which includes compliance with the requirements and restrictions listed in the informed consent form and in this protocol.
  • have access to a SmartPhone or tablet to utilize the mobile health app and/OR access the virtual classroom.
  • agree to undergo psychometric testing and participate in ongoing assessments throughout the study duration.
  • be willing to comply with all study procedures, able to complete all assessments independently, and available for the duration of the study.
Exclusion Criteria
  • Active suicidal ideation as assessed by the Investigator at screening or as identified during the study.
  • Clinically significant history of psychotic disorder, bipolar spectrum disorder, or neurodegenerative disease/dementia as assessed by the Investigator.
  • Active severe substance abuse as assessed by the investigator in accordance with DSM-5 Substance Abuse Disorder criteria, an AUDIT score > 15, or partial Brief Addiction Monitor (BAM) indicating the presence of illicit substance use other than cannabis (< 3 times weekly).
  • They are currently undergoing another form of treatment other than supportive therapy (> 2 times per month).
  • Engaged in active trauma-focused therapy including Cognitive Processing Therapy (CPT)Prolonged Exposure (PE), or Eye Movement Desensitization and Reprocessing (EMDR).
  • Any other condition/situation that the Investigator believes may interfere with participant safety, study conduct, or interpretation of study data.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
SIT NAVIGATOR only groupSIT NAVIGATOR-
SIT NAVIGATOR plus Stress NAVIGATOR groupStress NAVIGATOR (Mobile Health Application)-
SIT NAVIGATOR plus Stress NAVIGATOR groupSIT NAVIGATOR-
Primary Outcome Measures
NameTimeMethod
Change in average heart rate as assessed by the emWave Inner Balance personal biofeedback device by HeartMathBaseline , 4-6 weeks(mid treatment), end of treatment (11-14 weeks)

Heart rate is measured in beats per minute

Change in achievement score as assessed by the emWave Inner Balance personal biofeedback device by HeartMathBaseline , 4-6 weeks(mid treatment), end of treatment (11-14 weeks)

Achievement is measured via mathematical equation that includes coherence and heart rate variability and beats per minute over time. Higher achievement is associated with higher coherence sustained over time.

Satisfaction with care as assessed by the Client Satisfaction Questionnaire (8-item; CSQ-8)end of study (about 11-14 weeks after baseline)

This is an 8 item questionnaire , each is scored on a 4-point Likert scale where 1 indicates low satisfaction with care (e.g., quite dissatisfied,poor) and 4 indicates high satisfaction with care (e.g., very satisfied, excellent). for a score range of 8-32, higher score indicating better outcome

Patient satisfaction as assessed by the Client Satisfaction Questionnaire (8-item; CSQ-8)end of treatment (11-14 weeks)

The CSQ-8 is an 8-item measurement of global satisfaction. The range of possible scores is 8-32; higher scores indicate higher satisfaction with treatment. Items are measured on a 4-point Likert scale where 1 indicates low satisfaction with care (e.g., quite dissatisfied, poor) and 4 indicates high satisfaction with care (e.g., very satisfied, excellent).

Increasing resilience as assessed by The Connor-Davidson Resilience Scale-10 (CD-RISC-10)4end of study (about 11-14 weeks after baseline)

This is a 10 item questionnaire , each is scored from 0(not true at all) to 4(true nearly all the time) for a maximum score of 40, higher score indicating better outcome

Reduced symptoms of PTSD as assessed by the Posttraumatic Stress Disorder Checklist for Diagnostic and Statistical Manual of Mental Disorders (DSM-5) (PCL-5)end of study (about 11-14 weeks after baseline)

This is a 20 item questionnaire , each is scored from 0(not at all) -4( extremely)for a maximum score of 80, higher score indicating worse outcome

Satisfaction with care as assessed by the Client Satisfaction Questionnaire-8-item (CSQ-8)4 weeks after baseline

This is an 8 item questionnaire , each is scored on a 4-point Likert scale where 1 indicates low satisfaction with care (e.g., quite dissatisfied,poor) and 4 indicates high satisfaction with care (e.g., very satisfied, excellent). for a score range of 8-32, higher score indicating better outcome

Satisfaction with care as assessed by the Client Satisfaction Questionnaire-8 item ( CSQ-8)8 weeks after baseline

This is an 8 item questionnaire , each is scored on a 4-point Likert scale where 1 indicates low satisfaction with care (e.g., quite dissatisfied,poor) and 4 indicates high satisfaction with care (e.g., very satisfied, excellent). for a score range of 8-32, higher score indicating better outcome

Change in average coherence(heart rate variability) as assessed by the emWave Inner Balance personal biofeedback device by HeartMathBaseline , 4-6 weeks(mid treatment), end of treatment (11-14 weeks)

Heart rate variability is measured via a mathematical algorithm called coherence

Secondary Outcome Measures
NameTimeMethod
Change in difficulty to fall sleep as assessed by the Insomnia Severity Index (ISI)Baseline , 4-6 weeks(mid treatment), end of treatment (11-14 weeks)

This is a 7 item questionnaire, with a score range from 0-28, higher score indicating more insomnia

Change in severity of depression as assessed by the Patient Health Questionnaire (PHQ-9)Baseline , 4-6 weeks(mid treatment), end of treatment (11-14 weeks)

9 item questionnaire and each is scored from 0(not at all) to 3(nearly every day) for a maximum score of 27, higher score indicating worse outcome

Change in pain interference as assessed by the Patient-Reported Outcomes Measurement Information System (PROMIS)-Pain Interference scaleBaseline , 4-6 weeks(mid treatment), end of treatment (11-14 weeks)

This is a 6 item questionnaire and each is scored from 1(not at all) to 5(very much) for a maximum score of 30, higher score indicating more pain interference

Change in pain intensity as assessed by the Patient-Reported Outcomes Measurement Information System (PROMIS)-Pain Intensity scaleBaseline , 4-6 weeks(mid treatment), end of treatment (11-14 weeks)

This is a 3 item questionnaire and each is scored from 1(had no pain) to 5(severe pain) for a maximum score of 15, higher score indicating more pain

Change in adaptability to stress as assessed by the Situational Adaptation to Stress Scale (SASS-HSR)Baseline , 4-6 weeks(mid treatment), end of treatment (11-14 weeks)

This is an 18 item questionnaire and each is scored from 1( totally disagree) to 5 (agree) for a maximum score of 90, higher score indicating better outcome

Trial Locations

Locations (1)

The University of Texas Health Science Center at Houston

🇺🇸

Houston, Texas, United States

© Copyright 2025. All Rights Reserved by MedPath