Effects of early used Shenfu injection on hemodynamics in patients with sepsis: a multicenter, randomized, controlled trial
- Conditions
- Sepsis
- Registration Number
- ITMCTR2200006148
- Lead Sponsor
- Zhongnan Hospital of Wuhan University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1.Meet the diagnostic criteria for sepsis (sepsis 3.0)
2.Age: 18-75 years old
1.Expected ICU stay is less than 24 hours
2.Diagnosed with sepsis for more than 24 hours
3.Diagnosed with obstructive shock
4.Cardiogenic shock caused by acute myocardial infarction, valvular heart disease, dilated cardiomyopathy, restrictive cardiomyopathy, etc
5.History of CPR or advanced malignant tumor
6.Allergy history of Shenfu injection
7.Pregnant or breastfeeding women
8.Severe liver and kidney damage, requiring blood purification during the study
9.Use of immunomodulators or organ transplantation within 6 months
10.Participated in other clinical trials in the past three months
11.Use of other traditional Chinese medicines during the study
12.Other special circumstances are excluded by the clinical staff at the time of registration
13.If a patient misdiagnosed with sepsis is identified, he/she should be removed after enrollment
Patients with the following conditions will be withdrawn:(1)leaving the ICU without authorization;(2)incomplete follow-up;(3)poor compliance.
Document the reasons for the patient's withdrawal from the study.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method