NCT02306668
Unknown
Not Applicable
Microbiome Analysis of the Ocular Surface in Dry Eye Disease
ConditionsDry Eyes
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Dry Eyes
- Sponsor
- University of Washington
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Identification of bacteria or fungus from conjunctival swab
- Last Updated
- 11 years ago
Overview
Brief Summary
The investigators seek to characterize the identity of all microorganisms residing on the eye's surface (conjunctiva) in healthy eyes and those with dry eye syndrome, using a combination of analyses. Dry eye disease is thought to have an inflammatory basis and in the vast majority of cases the cause of the chronic inflammatory condition is unknown.
Investigators
Russell Van Gelder
Professor and Chair, Department of Ophthalmology
University of Washington
Eligibility Criteria
Inclusion Criteria
- •dry eye syndrome with OSDI score greater than 60
- •control group with OSDI score less than 30
Exclusion Criteria
- •recent history of contact lens wear
- •use of topical antibiotics or prescription eye medication in past 6 months
- •penetrating ocular surgery in the last 12 months
- •age less than 18 years
Outcomes
Primary Outcomes
Identification of bacteria or fungus from conjunctival swab
Time Frame: 1 month
Study Sites (1)
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