跳至主要内容
临床试验/NCT02306668
NCT02306668Unknown不适用

Microbiome Analysis of the Ocular Surface in Dry Eye Disease

University of Washington1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2014年2月最近更新:
适应症

试验速览

阶段
不适用
入组人数
80
试验地点
1
主要终点
Identification of bacteria or fungus from conjunctival swab

研究概览

简要总结

The investigators seek to characterize the identity of all microorganisms residing on the eye's surface (conjunctiva) in healthy eyes and those with dry eye syndrome, using a combination of analyses. Dry eye disease is thought to have an inflammatory basis and in the vast majority of cases the cause of the chronic inflammatory condition is unknown.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • dry eye syndrome with OSDI score greater than 60
  • control group with OSDI score less than 30

排除标准

  • recent history of contact lens wear
  • use of topical antibiotics or prescription eye medication in past 6 months
  • penetrating ocular surgery in the last 12 months
  • age less than 18 years

结局指标

主要结局

Identification of bacteria or fungus from conjunctival swab

时间窗: 1 month

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Russell Van Gelder

Professor and Chair, Department of Ophthalmology

University of Washington

研究点 (1)

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