NCT02306668Unknown不适用
Microbiome Analysis of the Ocular Surface in Dry Eye Disease
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Identification of bacteria or fungus from conjunctival swab
研究概览
简要总结
The investigators seek to characterize the identity of all microorganisms residing on the eye's surface (conjunctiva) in healthy eyes and those with dry eye syndrome, using a combination of analyses. Dry eye disease is thought to have an inflammatory basis and in the vast majority of cases the cause of the chronic inflammatory condition is unknown.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •dry eye syndrome with OSDI score greater than 60
- •control group with OSDI score less than 30
排除标准
- •recent history of contact lens wear
- •use of topical antibiotics or prescription eye medication in past 6 months
- •penetrating ocular surgery in the last 12 months
- •age less than 18 years
结局指标
主要结局
Identification of bacteria or fungus from conjunctival swab
时间窗: 1 month
次要结局
未报告次要终点
研究者
Russell Van Gelder
Professor and Chair, Department of Ophthalmology
University of Washington
研究点 (1)
Loading locations...
相似试验
招募中
不适用
Assessment of the Ocular Microbiome in Health and DiseaseMicrobial ColonizationEye DiseasesOphthalmopathyNCT05414994Vanderbilt University Medical Center500
招募中
不适用
Microbiological investigation of the ocular surface flora in the patients with strabismus surgery and prophylactic antibiotic eye dropsstrabismusJPRN-UMIN000041741Miyata eye Hospital100
已完成
不适用
Ocular Surface Microbiome in Dry Eye PatientsDry EyeNCT02161341Singapore National Eye Centre82
招募中
不适用
Microbiome analysis of ocular surface diseasesOcular surface diseasesJPRN-UMIN000032132Kochi University, Kochi Medical School, Department of Ophthalmology90
招募中
不适用
Analysis of Ocular Surface Microbiota in Dry Eye Patients After Femtosecond Laser-assisted In-situ Keratomileusis (FS-LASIK)Refractive SurgeryNCT06448468Second Affiliated Hospital of Nanchang University200
