NCT02344953Unknown不适用
Prospective and Retrospective Cohort Study of New Prognostic Factors With Peripheral Blood and Bone Marrow Evaluation at the Time of Diagnosis and During Treatment or Thereafter in Acute Leukemia (Acute Leukemia HSCT Cohort)
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Overall survival
研究概览
简要总结
The objective of this study is to evaluate the prognostic factors of acute leukemia patients received stem cell transplantation and to invent the molecular genetic test for sensitive detection of minimal residual disease, and thereby this study would contribute to plan the risk adapted treatment. Patients will have samples of blood and/or bone marrow collected during treatment or thereafter
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 16 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients diagnosed with acute leukemia who underwent allo-HSCT in Severance Hospital.
- •Both genders of 16 Years and older
- •sign a written informed consent document
- •exemption of consent in patient who died in study period.
排除标准
- •No comprehension or willingness to sign a written informed consent document.
结局指标
主要结局
Overall survival
时间窗: 10years
Overall survival (OS) is defined as the time from date of diagnosis until death due to any cause within the follow-up period. Surviving patients are censored at date of last contact.
次要结局
- Progression-free survival(10years)
- Treatment-related mortality(10years)
- Complete remission rate(10 years)
研究者
研究点 (1)
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