Clinical Values of Mature Fistulas in Hemodialysis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hemodialysis Access Failure
- Sponsor
- Shanghai Zhongshan Hospital
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- AVF patency
- Last Updated
- 5 years ago
Overview
Brief Summary
The arteriovenous fistula (AVF) is the preferred vascular access for hemodialysis(HD), and fistula-first is the general recommendation for all HD patients. But in clinical practice in China, quite a few patients start HD before AVF maturation due to various situations. Whether HD initiation with mature AVF will influence the patency and complications is controversial. This study is aim to compare the AVF patency in incident HD patients with mature or immature AVF on HD initiation, and to compare other clinical outcomes, including abandonment without use, infection, and other AVF complications occurrence.
Investigators
Bo Shen
Principal Investigator
Shanghai Zhongshan Hospital
Eligibility Criteria
Inclusion Criteria
- •underwent initial upper-extremity AVF creation for incident HD at Zhongshan Hospital, Fudan University
Exclusion Criteria
- •with malignancies
- •not followed-up at Zhongshan Hospital, Fudan University
Outcomes
Primary Outcomes
AVF patency
Time Frame: June 2020 to June 2021
A functional AVF was defined as allowing at least six adequate HD sessions without any AVF-related complications. Primary AVF patency was defined as the interval from HD initiation via a functional AVF to any intervention designed for maintenance or reestablishment of AVF function, AVF failure, or study end, whichever occurred first, and secondary AVF patency was defined as the interval from HD initiation via an AVF until the termination of HD via AVF due to any cause, regardless of the number of subsequent interventions.
Secondary Outcomes
- Abandonment without use, infection, and other complications of AVF creation.(June 2020 to June 2021)