Identification of a marker in skin called anti-IgE antibody by microscopy in patients with a blistering disease of skin known as bullous pemphigoid
Not Applicable
- Conditions
- Health Condition 1: L120- Bullous pemphigoid
- Registration Number
- CTRI/2024/05/067574
- Lead Sponsor
- Kasturba Medical College Manipal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients with a clinical diagnosis consistent with bullous pemphigoid as per the standard diagnostic criteria.
2. Direct immunofluorescence (DIF) microscopy showing linear deposits of IgG and/or Complement C3 along the basement membrane zone.
3. Indirect immunofluorescence (IIF) of salt-split skin biopsy showing deposition of IgG along the basement membrane zone, if done.
Exclusion Criteria
1. Severe bleeding and coagulation disorders.
2. Failure to obtain written informed consent for skin biopsy.
3. Severely immunosuppressed conditions, including acquired immunodeficiency syndrome (AIDS).
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method