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临床试验/NCT02827357
NCT02827357已完成不适用

Review of Responses to Systemic Chemotherapy of Patients With Non-small Cell Lung Cancer Harboring a Known Somatic Activating HER2 Mutation

University Hospital, Toulouse0 个研究点目标入组 101 人开始时间: 2013年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
101
主要终点
Overall response rate

研究概览

简要总结

This chart review describe the response to systemic chemotherapy of patients with non-small cell lung cancer (NSCLC) harbouring a known somatic activating human epidermal growth factor receptor 2 (HER2) mutation. The analysis of this data will provide an initial description of the response to systemic chemotherapy in patients with NSCLC harboring an activating HER2 mutation in order to inform the design and powering of future randomized controlled clinical trials of HER2-directed therapy.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients with advanced nonsmall-cell lung cancer
  • known HER2 exon-20 insertion
  • treated with chemotherapy and/or HER2-targeted drugs

排除标准

  • 未提供

结局指标

主要结局

Overall response rate

时间窗: 24 months

次要结局

  • Median progression-free survival (PFS) with conventional chemotherapy(24 months)

研究者

申办方类型
Other
责任方
Sponsor

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