Sleep benefit in Parkinson's disease: The influence of sleep on motor performance and cognitive flexibility

Completed

Conditions: Parkinson's disease
10028037

Registration Number: NL-OMON36932

Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 60

Inclusion Criteria

Idiopatic Parkinson's disease (patients)
Hoehn & Yahr stage II-III (patients)
able to take an afternoon nap (patients and controls)

Exclusion Criteria

Neurological diease (for patients; other than Parkinson's disease)
Current psychiatric diagnosis (including depression)
MMSE < 24 (patients), MMSE < 28 (controls)
color blindness
Chronic daily use of sleep medication

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>* The difference between post-nap and pre-nap performance on the pegboard<br /><br>dexterity test.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary:<br /><br><br /><br>* The difference between post-nap and pre-nap performance on the task-switching<br /><br>task.<br /><br><br /><br>Other:<br /><br><br /><br>Objective:<br /><br>* The difference between post-nap and pre-nap performance on the finger<br /><br>tappingtask.<br /><br>* The difference between post-night sleep and pre-night sleep performance on<br /><br>the motor tasks (pegboard dexterity test and finger tapping).<br /><br>* The difference between post-night sleep and pre-night sleep performance on<br /><br>the task-switching task.<br /><br>* Sleep outcomes as measured by polysomnography<br /><br><br /><br>Subjective:<br /><br>* The difference between post-nap and pre-nap ratings on subjective functioning<br /><br>and mood.<br /><br>* The difference between post-night sleep and pre-night sleep ratings on<br /><br>subjective functioning and mood.</p><br>