Does the oral nutritional supplementation of undernourished older people after hospital discharge improve muscle function? A two centre double blind placebo controlled trial
Not Applicable
Completed
- Conditions
- ndernourished older people admitted with an acute illnessNutritional, Metabolic, EndocrineNutritional supplementation
- Registration Number
- ISRCTN33287248
- Lead Sponsor
- niversity of Dundee (UK)
- Brief Summary
2009 results in http://www.ncbi.nlm.nih.gov/pubmed/19925613
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 320
Inclusion Criteria
1. Age 70 years and over
2. Community dwelling
3. Admitted to hospital with an acute illness
4. Body mass index =24 kg/m^2
5. Mid-arm muscle circumference below the 10th centile and/or weight loss of 5% or more during hospital stay
Exclusion Criteria
1. Chronic liver diease or renal failure
2. Nursing home residents
3. Cognitive impairment precluding informed consent
4. Dysphagia
5. Metastatic carcinoma or other terminal illness
6. Pathology such as inflammatory arthritis or stroke affecting non-dominant handgrip
7. Major surgery within one month
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Changes in muscle strength (handgrip dynamometry)<br>2. Changes in disability (Barthel index)
- Secondary Outcome Measures
Name Time Method 1. Changes in lower limb muscle strength<br>2. Changes in weight<br>3. Changes in dietary intake (24 hour dietary recall)<br>4. Changes in daily physical activity levels (accelerometry)<br>5. Changes in health related quality of life (Euroquol)<br>6. Unplanned hospital readmissions