Effects of i.v.Dexmedetomidine on Spinal Anaesthesia in Lower Limb Orthopaedic Surgeries.
- Conditions
- Disorder of continuity of bone, unspecified,
- Registration Number
- CTRI/2019/10/021662
- Lead Sponsor
- MALLIDI CHANDRASEKHARA REDDY
- Brief Summary
—Orthopaedic procedures of lower limbs are best doneunder spinal anaesthesia but the major problem is positioning the patient forspinal block
—Due to the injury and pain, longer time is taken forpositioning and to achieve a successful Dural tap.
—The discomfort and distress of positioning requiresprior administration of strong IV narcotics, which have the disadvantage ofover sedation, respiratory depression & poor co-operation
—Dexmedetomidine is a very potent a2 agonist which causesdose dependent sedation, anxiolysis ,some analgesia, blunting stress responseand also with opioid sparing effect
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 100
Asa status 1&2 Patients undergoing lower limb orthopedic surgery.
PATIENTS WITH SINUS BRADYCARDIA PATIENTS WITH ARRYTHMIA ANY CONTRAINDICATIONS FOR SPINAL ANAESTHESIA HISTORY OF DRUG HYPERSENSITIVITY PATIENTS REFUSAL.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration for conducting the spinal block Level of sensory block and quality of motor block at 5 min of spinal anaesthesia till 15 minutes. |  Time for two segment regression after completion of surgical procedure. |  Level of sedation (Ramsay sedation score) at 15minutes interval till the patient discharge from post anaesthesia care unit or fully alert. | Post operative pain ( VAS score), time to requirement of 1st rescue analgesia, and total rescue doses in first 24 hours Quality and duration of spinal block Level of sensory block and quality of motor block at 5 min of spinal anaesthesia till 15 minutes. |  Time for two segment regression after completion of surgical procedure. |  Level of sedation (Ramsay sedation score) at 15minutes interval till the patient discharge from post anaesthesia care unit or fully alert. | Post operative pain ( VAS score), time to requirement of 1st rescue analgesia, and total rescue doses in first 24 hours Post operative pain & analgesia requirement Level of sensory block and quality of motor block at 5 min of spinal anaesthesia till 15 minutes. |  Time for two segment regression after completion of surgical procedure. |  Level of sedation (Ramsay sedation score) at 15minutes interval till the patient discharge from post anaesthesia care unit or fully alert. | Post operative pain ( VAS score), time to requirement of 1st rescue analgesia, and total rescue doses in first 24 hours SPINAL BLOCK. Level of sensory block and quality of motor block at 5 min of spinal anaesthesia till 15 minutes. |  Time for two segment regression after completion of surgical procedure. |  Level of sedation (Ramsay sedation score) at 15minutes interval till the patient discharge from post anaesthesia care unit or fully alert. | Post operative pain ( VAS score), time to requirement of 1st rescue analgesia, and total rescue doses in first 24 hours POST OPERATIVE PAIN AND ANALGESIA REQUIREMENT. Level of sensory block and quality of motor block at 5 min of spinal anaesthesia till 15 minutes. |  Time for two segment regression after completion of surgical procedure. |  Level of sedation (Ramsay sedation score) at 15minutes interval till the patient discharge from post anaesthesia care unit or fully alert. | Post operative pain ( VAS score), time to requirement of 1st rescue analgesia, and total rescue doses in first 24 hours
- Secondary Outcome Measures
Name Time Method Level of sedation Hemodynamic changes
Trial Locations
- Locations (1)
kalinga Institute of Medical Sciences
🇮🇳Khordha, ORISSA, India
kalinga Institute of Medical Sciences🇮🇳Khordha, ORISSA, Indiamallidi chandrasekhara reddyPrincipal investigator6309547889healing.chandu@gmail.com