EUCTR2020-002579-37-IT进行中（未招募）1 期
Metformin as maintenance therapy in bone sarcomas at high risk of relapse - Metformin-Bone
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- Age = 14 years
- •- Patients with localized osteosarcoma with necrosis = 60% at the end of postoperative chemotherapy (within 45 days)
- •- Patients with osteosarcoma or Ewing's Sarcoma made disease-free after the first relapse (within 45 days of surgery or chemotherapy)
- •- Patients not included in other protocols
- •- Patients who can swallow
- •- Screening within 30 days after the end of chemotherapy (or relapse surgery).
- •- Start of treatment within 30 minutes after screening
- •- Normal renal function (creatinine <1.3, creatinine > 60) and liver function (serum bilirubin <1.4, AST and ALT <1.8) above the normal range.
- •Are the trial subjects under 18? yes
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 60
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •- Type I or II diabetes
- •- Patient with metastatic disease
- •- Patients with kidney failure of any degree
- •- Patient who does not meet the inclusion criteria
研究者
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