A comparison of oesophageal Doppler with arterial pressure waveform derived cardiac output and stroke volume variation for the assessment of haemodynamic state in adult patients undergoing major surgery.

Not Applicable

Completed

• Conditions: Hypovolemia; Major surgery with significant blood loss; Anaesthesiology - Anaesthetics

• Registration Number: ACTRN12609000407291
• Lead Sponsor: Anaesthetic Department, St Vincent's Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-06-02
• Study Completion: 2009-10-09
• Last Update Posted: 15 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 39

Inclusion Criteria

Major surgery with significant blood loss (estimated >500mls)

Exclusion Criteria

Contraindication to an oesophageal probe such as varices or peptic ulcer disease.
Atrial Fibrillation, Aortic regurgitation

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Accuracy of these cardiac output monitors.<br><br>This will be assessed in a number of ways. <br>For static error, we will use bias and variation compared to thermodilution for each of the devices. A standard representation method is Bland Altman analysis.[Intraoperative]

Secondary Outcome Measures

Name	Time	Method
Ability to track changes in cardiac output.<br>For dynamic error, we will use event analysis. Here, we will use mean and variation for change of cardiac ouput for an event such as fluid administration. We will subject the data to an appropriate test of statistical significance. This will enable us to determine if there is a difference in the way these machines track event changes.[Intraoperative]