The study of pneumococcal nasal carriage and the economic evaluation of pneumococcal vaccine in Thai elderly

Completed

• Conditions: elderly with predisposing invasive pneumococcal infection conditions; pneumococcal colonization, pneumococcal vaccine

• Registration Number: TCTR20210604004
• Lead Sponsor: Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-06-04
• Study Completion: 2022-09-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

1.All participants criteria are Male and Female, Age 65 years old or above, and are willing to participate in the study., 2. Participants stay in nursing home at least 2 years27 before enrollment., 3. Participants from nursing home who are unable to consent can be enrolled in accordance with legal guardian acceptance. 4. Participants who had chronic health conditions are as follows; chronic heart, lung, kidney or liver disease, diabetes, previous stroke, any types of autoimmune disease, any types of cancer or any types of immunodeficiency conditions. 5. Participants from hemodialysis unit should receive renal replacement therapy at least 3 months before enrollment.

Exclusion Criteria

Unable to obtain nasopharyngeal sample, for example, nasopharynx structure abnormal, neutropenia or history of surgery at nasopharynx or base of skull.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
pneumococcal colonization at screening PCR/ conventional,pneumococcal serotype at screening PCR/ conventional

Secondary Outcome Measures

Name	Time	Method
pneumococcal colonization in covid-19 at screening PCR/ conventional