Randomized, double-blind, placebo-controlled parallel-group comparative study to evaluate the effects of resveratrol dimer from melinjo (Gnetum gnemon) on the adiponectin and its-related molecules among healthy adult males
Not Applicable
- Conditions
- Obesity
- Registration Number
- JPRN-UMIN000025643
- Lead Sponsor
- Division of Pharmacology and Therapeutics, Graduate School of Pharmaceutical Sciences, Kumamoto University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Male
- Target Recruitment
- 42
Inclusion Criteria
Not provided
Exclusion Criteria
1) An allergy to melinjo and any medicine or food 2) A history of any infectious disease with in 4 weeks before enrolment 3) The use of any investigational drugs within 3 months 4) The use of melinjo or medicines within 2 weeks before enrolment 5) The use of prescription or over-the-counter medications or alcohol within 2 days before enrolment 6) Consumption of functional foods related to lipid and glucose metabolism 7) Regularly drinking red wine 8) Preexisting liver, renal, lung, gastrointestinal tract or heart disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The effects of melinjo seed extract administration for 2 weeks on the DsbA-L activity
- Secondary Outcome Measures
Name Time Method DsbA-L mRNA PPAR activity and mRNA Adiponectin activity HMW adiponectin activity