The Effect of Pre-treatment Biopsy for Non-neoplastic Renal Disease vs no Biopsy on Estimated Glomerular Filtration Rate in Patients With Small Renal Mass: a Single-center, Single-blinded, Randomized, Parallel Group Clinical Trial
Not Applicable
Withdrawn
- Conditions
- Kidney Neoplasms
- Registration Number
- NCT02841020
- Lead Sponsor
- University of Virginia
- Brief Summary
The purpose of this study is to determine if biopsy for non-neoplastic renal disease for patients with a small renal mass results in greater postoperative renal function than the current standard of care (no additional biopsy).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Age 18 or greater
- Scheduled for renal biopsy as part of clinical care
- Diagnosis of small renal mass (< 4cm) based on imaging (CT, MRI, Ultrasound, or other)
- Patient must provide written, informed consent for study procedures before randomization
- Renal mass must be primarily solid (as opposed to cystic) in nature
Exclusion Criteria
- Patients less than 18 years of age
- Patients who are prisoners
- Women who are pregnant-self reported
- Patients with Bosniak 3 or 4 cystic renal masses
- Patients with history of renal transplantation
- Patients with eGFR less than 30-based on review of clinical labs
- Patients on dialysis
- Patients with bleeding disorders
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method difference in change in glomerular filtration rate (GFR) 6 months
- Secondary Outcome Measures
Name Time Method