ong-term intervention study of bone density maintenance and lifestyle-related disease prevention by daily lemon intake in Japanese men and women who lives in Osaki-Kamijima, Hiroshima
Not Applicable
Recruiting
- Conditions
- one
- Registration Number
- JPRN-jRCTs031200031
- Lead Sponsor
- Takara Tsuyoshi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 800
Inclusion Criteria
1. Participants who have received a sufficient explanation of the purpose and contents of this test, have sufficient consent ability, have a thorough understanding, apply voluntarily, and have agreed to participate in writing.
2. Japanese adults over the age of 20
3. Participants who live in Osaki Kamijima Town, Hiroshima Prefecture
Exclusion Criteria
1. Participants with a history of serious illness
2. Participants who have allergic to the test food
3. Participants who judged by the investigator to be inappropriate as subjects
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bone density (assessed by dual-energy X-ray absorptiometry)
- Secondary Outcome Measures
Name Time Method Blood tests: (Red blood cell count, hemoglobin, hematocrit, total protein, albumin, total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol, AST, ALT, ALP, gamma-GTP, CPK, creatinine, uric acid, glucose, HbA1c (NGSP), osteocalcin (BGP), bone tartrate-resistant acid phosphatase (TRACP-5b), bone alkaline phosphatase (BAP))<br>Urinalysis: (glucose, protein, sodium, creatinine, salt intake volume)<br>Physical measurements: (sleep, weight, BMI, blood pressure, pulse, abdominal circumference)<br>Questionnaire survey: (Basic survey on sleep, fatigue, lemon intake record, diet, medical history, dispensing information, etc.)