Identification of resting brain functional connectivity markers of response to continuous Theta Burst Stimulation and cathodal transcranial Direct Current Stimulation in schizophrenia patients with persistent auditory hallucinations

Department of Psychiatry National Institute of Mental Health and Neuro Sciences0 个研究点目标入组 0 人开始时间: 待定最近更新: 2022年10月17日

试验速览

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•1.Schizophrenia Diagnosis (DSM-5);
•2.Right-Handedness [Edinburgh Handedness Inventory);
•3.Persistence of auditory hallucinations without remission despite treatment with at least one antipsychotic medication at an adequate dose for a minimum period of six weeks.
•4.Non-remission defined as a score of moderate or high ( >2) on the Global Rating of Hallucinations in the scale for the assessment of positive symptoms.
•5.Capacity to consent for research studies as per the assessment using the University of California, San Diego Brief Assessment of Capacity to Consent (UBACC)
•6.Written informed consent.

•1.Psychiatric emergency necessitating electroconvulsive therapy;
•2.Suicidal risk / any psychiatric emergency;
•3.Score of > 6 on Calgary Depression Rating Scale
•4.Pregnancy / Post-Partum;
•5.Substance use disorder in last six months (except caffeine or nicotine);
•6.Co-morbid neurological/medical disease that can affect the brain structure/function;
•7.Any Contraindication for Magnetic Resonance Imaging;
•8.Any Contraindication for Transcranial Magnetic Stimulation;
•9.Any Contraindication for Transcranial Direct Current Stimulation

发起方

Department of Psychiatry National Institute of Mental Health and Neuro Sciences