IRCT2014050511375N3
Completed
Phase 3
The Effect of Angiotensin Converting Enzyme Inhibitor on the Quality of Life of Non Hospitalized Patients With Cancer Cachexia
Shiraz University of Midical Sciences0 sites40 target enrollmentTBD
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Gastric cancer.
- Sponsor
- Shiraz University of Midical Sciences
- Enrollment
- 40
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Inclusion Criteria: Patients with aged 40\-80 years old; Patients with BMI less 18 and those with muscle wasting or only temporal wasting.
Exclusion Criteria
- •Patients unable to continue the treatment; Patients with BMI more 18 without temporal or muscle wasting; Those with GFR less 50 ml/min; Positive history of other co\-morbidity diseases; Patients with Hb less 9; Patients unavailable for or incapable of filling out questionnaires at different intervals.
Outcomes
Primary Outcomes
Not specified
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Angiotensin Converting Enzyme Inhibitor (ACE) Induced AngioedemaBERINERTRandomized, double-blind, two arms, multicenter, Phase III study of Berinert for treatment of ACE induced AngioedemaAngiotensin – Converting – Enzyme – Inhibitors (ACEi) are used in the treatment of several types of cardiovascular and renal diseases. A known side effect of ACEi are angioedema of the head and neck region. These can lead to severe dyspnoea and the need for intubation and are thought to be bradykinin mediated. Up until now there is no study-evaluated conservative therapeutic concept for the treatment of these patients.MedDRA version: 18.1Level: HLTClassification code 10002425Term: AngioedemasSystem Organ Class: 100000004870Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08]EUCTR2012-001670-28-DEMedizinische Fakultät der Technischen Universität München52