NL-OMON38824
Completed
Not Applicable
Towards an individualized treatment of patients with disorders of aggression regulation; endophenotypes of aggressive behavior. - Endophenotypes of Aggressive Behavior
niversitair Medisch Centrum Sint Radboud0 sites154 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- aggression regulation disorder
- Sponsor
- niversitair Medisch Centrum Sint Radboud
- Enrollment
- 154
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Age 18\-55 years
- •\- Men and women
- •\- Outpatient
- •\- Meeting DSM\-IV criteria for antisocial personality disorder, borderline personality disorder or the integrated research criteria for Intermittent Explosive Disorder (IED\-IR):
- •\- Recurrent incidents of aggression manifest as either;
- •Verbal or physical aggression towards other people, animals, or property occurring twice weekly
- •on average for one month, or
- •\- Three episodes involving physical assault against other people or destruction of property over one\-year period
- •\- The degree of aggressiveness expressed is grossly out of proportion to the provocation or any precipitating psychosocial stressors
- •\- The aggressive behavior is generally not premeditated (e.g., is impulsive) and is not committed in order to achieve some tangible objective (e.g., money, power, intimidation, etc.)
Exclusion Criteria
- •\- Lifetime history of (hypo)mania, schizophrenia, or delusional disorder
- •\- Current major depression
- •\- Current alcohol or substance dependence
- •\- Starting or changing pharmacotherapy relating to aggressive behavior
Outcomes
Primary Outcomes
Not specified
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