Preconceptional transvaginal cervicoisthmic cerclage versus transvaginal cervicoisthmic cerclage in pregnancy for the prevention of preterm delivery in women with cervical insufficiency: a randomized controlled study

Health Bureau of Zhejiang Province0 sites200 target enrollmentJanuary 14, 2015

Overview

No summary available.

Registry

who.int

Start Date

January 14, 2015

End Date

December 31, 2020

Last Updated

7 years ago

Study Type

Interventional

Sex

Female

Sponsor

Health Bureau of Zhejiang Province

•Current inclusion criteria as of 04/03/2019:
•1\. A history of at least 1 previous late inevitable abortion or spontaneous preterm delivery
•2\. Previous conization of the cervix or cervical laceration by assisted vaginal delivery, and the residual cervix is less than 25mm
•3\. All patients should be \>\=18 years and younger than 35 years old
•4\. All patients are able to conceive
•Previous inclusion criteria:
•1\. A history of at least 2 previous late inevitable abortion or spontaneous preterm delivery
•2\. Previous conization of the cervix or cervical laceration by assisted vaginal delivery, and the residual cervix is less than 25mm
•3\. All patients should be \>\=18 years and younger than 35 years old
•4\. All patients are able to conceive

•1\. Older than 35 years old
•2\. Patients with a successful or failed cerclage applied in a previous pregnancy
•3\. Patients with congenital uterine dysplasia: Mediastinum uterus, bicornuate uterus, rudimentary horn of uterus, et al.
•4\. Patients with protein C, protein S, or antithrombin III de?ciency
•5\. Patients who are pregnant