Preconceptional transvaginal cervicoisthmic cerclage versus transvaginal cervicoisthmic cerclage in pregnancy for the prevention of preterm delivery in women with cervical insufficiency
- Conditions
- Cervical insufficiencyPregnancy and Childbirth
- Registration Number
- ISRCTN13763635
- Lead Sponsor
- Health Bureau of Zhejiang Province
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 200
Current inclusion criteria as of 04/03/2019:
1. A history of at least 1 previous late inevitable abortion or spontaneous preterm delivery
2. Previous conization of the cervix or cervical laceration by assisted vaginal delivery, and the residual cervix is less than 25mm
3. All patients should be >=18 years and younger than 35 years old
4. All patients are able to conceive
Previous inclusion criteria:
1. A history of at least 2 previous late inevitable abortion or spontaneous preterm delivery
2. Previous conization of the cervix or cervical laceration by assisted vaginal delivery, and the residual cervix is less than 25mm
3. All patients should be >=18 years and younger than 35 years old
4. All patients are able to conceive
1. Older than 35 years old
2. Patients with a successful or failed cerclage applied in a previous pregnancy
3. Patients with congenital uterine dysplasia: Mediastinum uterus, bicornuate uterus, rudimentary horn of uterus, et al.
4. Patients with protein C, protein S, or antithrombin III de?ciency
5. Patients who are pregnant
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> 1. The perinatal survival rate<br> 2. The delivery gestational age<br>
- Secondary Outcome Measures
Name Time Method <br> 1. Complications during pregnancy<br> 2. The fetal weight<br>