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临床试验/NCT07495462
NCT07495462已完成不适用

The Effect of Motor Imagery Added to Conventional Rehabilitation on Balance and Kinesiophobia in Patients With Parkinson's Disease: A Randomized Controlled Trial

Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital1 个研究点 分布在 1 个国家目标入组 42 人开始时间: 2026年1月2日最近更新:
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
42
试验地点
1

研究概览

简要总结

Parkinson's Disease (PD) is a progressive brain disorder that affects movement and balance. It can cause slowed movements, stiffness, tremor, balance problems, and an increased risk of falling. Many individuals with PD develop fear of movement, also referred to as kinesiophobia, and fear of falling. This condition may lead to avoidance of physical activity, which can further worsen balance and movement abilities.

This study aims to determine whether adding Motor Imagery (MI) to a standard rehabilitation program can improve balance and reduce fear of movement in individuals with PD. MI is a mental practice technique in which an individual rehearses movements cognitively without actual physical execution. For example, a person may imagine standing up, walking, or climbing stairs. Although the movement is not physically performed, the brain regions involved in movement are activated. MI is safe, does not require special equipment, and may help improve motor control.

Eligible participants will be randomly assigned to one of two groups. One group will receive standard physical therapy and rehabilitation exercises, while the other group will receive the same therapy combined with additional MI training. The rehabilitation program will last six weeks.

The study will primarily evaluate whether this combined approach improves balance and reduces fear of movement. In addition, the potential effects of the intervention on fall risk, functional mobility and performance, fear of falling, activities of daily living, and motor function will also be examined. Assessments will be performed at the beginning of the study, at the end of treatment, and again at 12 weeks.

Researchers hope to determine whether combining MI with conventional rehabilitation provides greater benefits than conventional rehabilitation alone and may help improve rehabilitation strategies for people living with PD.

详细描述

Parkinson's Disease (PD) is a progressive neurological disorder that affects movement control due to the gradual loss of dopamine-producing neurons. Over time, individuals may experience motor symptoms such as bradykinesia, rigidity, tremor, and impaired postural control. Among these symptoms, balance impairment and postural instability are major contributors to falls and increased fall risk. Falls are common in people with PD and may lead to injury and limitations in safe mobility.

In addition to motor symptoms, psychological factors may influence movement performance. One important factor is kinesiophobia, defined as an excessive fear of movement due to the belief that physical activity may cause falling or injury. Fear of falling may lead individuals to avoid movement and reduce participation in physical activities and rehabilitation programs. Reduced activity levels may contribute to muscle weakness, further balance deterioration, decline in functional performance, and worsening motor abilities. Therefore, rehabilitation strategies that address both motor impairments and movement-related fear are essential.

Conventional rehabilitation programs for PD typically include balance training, gait training, strengthening exercises, and functional mobility tasks. These interventions aim to improve postural control, reduce fall risk, and enhance motor performance. However, the effectiveness of rehabilitation may vary depending on patient engagement, motivation, and psychological readiness for movement.

Motor Imagery (MI) is a technique that involves mentally rehearsing a movement without physically performing it. Neurophysiological research indicates that MI activates neural pathways similar to those involved in actual movement execution. This activation may facilitate motor learning, improve coordination, and enhance balance control. Because MI does not require physical exertion, it may be particularly beneficial for individuals whose participation in physical exercise is limited by balance deficits or fear of falling.

Previous studies in neurological rehabilitation suggest that Motor Imagery (MI) may support improvements in motor performance and balance. However, limited evidence exists regarding its effectiveness in simultaneously improving balance and reducing movement-related fear in individuals with PD.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
40 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Diagnosis of Parkinson's Disease (PD)
  • Age 40 years or older
  • Modified Hoehn and Yahr scale stage between 1 and 3
  • Mini-Mental State Examination (MMSE) score of 22 or higher

排除标准

  • Presence of an additional neurological disorder
  • Movement impairment or nerve damage due to orthopedic pathology
  • Cardiopulmonary conditions that contraindicate exercise participation
  • Presence of severe dyskinesia
  • Visual or vestibular impairments that may affect balance
  • Presence of motor fluctuations (on-off periods)
  • Deep brain stimulation for Parkinson's Disease

研究组 & 干预措施

Motor Imagery + Conventional Rehabilitation Group

Experimental

Participants will receive traditional rehabilitation along with motor imagery training.

干预措施: Conventional Rehabilitation (Behavioral)

Conventional Rehabilitation Group

Active Comparator

Participants will receive a structured conventional rehabilitation program including balance training, gait training, strengthening exercises, and functional mobility exercises

干预措施: Conventional Rehabilitation (Behavioral)

Motor Imagery + Conventional Rehabilitation Group

Experimental

Participants will receive traditional rehabilitation along with motor imagery training.

干预措施: Motor Imagery Training (Behavioral)

研究者

发起方
Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
申办方类型
Other
责任方
Sponsor

研究点 (1)

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