Does Pre-washing the Catheter With a Culture Medium Before Intrauterine Insemination Have an Effect on Pregnancy Rates?
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 100
- Primary Endpoint
- Clinical pregnancy rate
Study Overview
Brief Summary
The aim of the study to evaluate the possible effect of washing the insemination catheters before intrauterine insemination on the pregnancy outcomes.
We know that washing the catheters are already washed in the case of embryo transfer for assisted reproductive techniques. Based on this knowledge, we also constituted the hypothesis which is about the impact of washing the catheter on the gametes and embryos. The pre-washing the catheter before intrauterine insemination may provide higher pregnancy results.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Other
- Masking
- Triple (Participant, Care Provider, Investigator)
Eligibility Criteria
- Ages
- 20 Years to 35 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •at least 1-year infertility
- •at least one patent fallopian tube confirmed by hysterosalpingography (HSG) or laparoscopy
- •ovulatory menstrual cycles
- •suitable semen analysis according to the World Health Organization (WHO) criteria for intrauterine insemination
Exclusion Criteria
- •bilateral tubal occlusion
- •mild or severe endometriosis
- •day 3 serum FSH (follicle-stimulating hormone) > 13 IU/L
- •abnormal thyroid function tests, hyperprolactinemia
- •total motile sperm count (TMSC) < 5 millions or severe teratospermia (<4% normal forms) following semen preparation
- •more than 3 follicles above the size of 17mm on the day of ovulation triggering
Outcomes
Primary Outcomes
Clinical pregnancy rate
Time Frame: 8 weeks after intrauterine insemination
Clinical pregnancy will be defined as the presence of a heartbeat at 6th gestational weeks
Secondary Outcomes
No secondary outcomes reported
Investigators
Vehbi Yavuz Tokgoz
Assocciate Professor
Eskisehir Osmangazi University