Assessment of Efficacy of Uterine Artery Doppler in Predicting the Response to Mefenamic Acid During Treatment of Women With IUCD Associated Menorrhagia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Women's Health: Amenorrhea/Dysmenorrhea
- Sponsor
- Ain Shams University
- Enrollment
- 156
- Locations
- 1
- Primary Endpoint
- Resistance index and Pulsitality index (Predicting the response to IUCD associated menorrhagia)
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
Studying the efficacy of uterine artery doppler in predicting response to mefenamic acid in women having IUCD associated menorrhagia
Investigators
Yasmine Essam Eldin Mohamed Mohamed Ismail
Principal investigator
Ain Shams University
Eligibility Criteria
Inclusion Criteria
- •women in chile bearing period (age 20-35 yrs ) with history of regular menstrual cycle presenting with recent onset of more then three months menorrhagia after IUCD "copper T 380 A" insertion
Exclusion Criteria
- •history of bleeding tendency
- •history of abnormal uterine bleeding due to other causes
- •history of active liver disease
- •history of antiplatelet or anticoagulant intake in the last month
- •history of thyroid disease
- •history of endometritis
- •history of allergy to NSAIDs
- •Adenomyosis
- •women having contraindications to use NSAIDs e.g. peptic ulcer
- •Insulin dependant diabetes mellitus
Outcomes
Primary Outcomes
Resistance index and Pulsitality index (Predicting the response to IUCD associated menorrhagia)
Time Frame: 1 year
Base line uterine artery doppler is done to the patient complaining of IUCD related menorrhagia prior to treatment , parameters of doppler are: resistance index and pulsitality index, then the patient takes mefenamic acid tablets 500 mg three times daily for five days, assessment of response whether the patient is responder or not is done using pictorial blood loss assessment chart then base line doppler parameters in responders and non responders are compared to correlate the response to base line doppler parameters