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临床试验/NCT06349018
NCT06349018已完成不适用

The Effects of Isotonic Beetroot Supplementation on Sprint Interval Exercise Performance.

Nanyang Technological University1 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2024年2月20日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
24
试验地点
1
主要终点
Power output during maximal sprint cycling

研究概览

简要总结

This study aims to examine the effects of dietary nitrate supplementation via beetroot juice on sprint interval cycling exercise performance. Twenty-four participants (male or female) will undertake a randomized, crossover trial where they consume either (i) an isotonic beetroot juice drink containing nitrate (12.9 mmol) for 5 days or (ii) an isotonic sports drink (no nitrate) for 5 days. On Day 5 of each trial, participants will come to the laboratory and 2 hours after consuming their allocated drink will complete a 6 bouts of sprint interval exercise. Power output during cycling will be measured as the primary outcome measure. Salivary and plasma measures of nitrate and nitrite will be taken over the course of the morning on Day 5. After a 5-day washout period participants will crossover and begin their second trial.

详细描述

This study aims to examine the effects of dietary nitrate supplementation via beetroot juice on sprint interval cycling exercise performance. Twenty-four participants (male or female) will undertake a randomized, crossover trial where they consume either (i) an isotonic beetroot juice drink containing nitrate (12.9 mmol) for 5 days or (ii) an isotonic sports drink (no nitrate) for 5 days. Drinks will be equivalent in isotonicity and colored the same so that participants and investigators will be blinded to each trial. Randomization and drink allocation will be completed by a third person not associated with the study team. On Day 5 of each trial, participants will come to the laboratory and 2 hours after consuming their allocated drink will complete a 6 bouts of sprint interval exercise (10 second all-out maximal sprints interspersed with 50 seconds rest). Power output (peak and mean) during cycling sprints will be measured as the primary outcome measure. Salivary measures of nitrate/nitrite will be taken at three time points over the course of the morning on Day 5 - (i) pre-drink consumption; (ii) 2 hours post-drink consumption; and (iii) post-exercise. Plasma measures of nitrate and nitrite will be taken at two time points over the course of the morning on Day 5 - (i) pre-drink consumption; and (ii) 2 hours post-drink consumption. Near infra-red spectroscopy (NIRS) will be used to measure muscle (vastus lateralis) oxygenation during cycling bouts. A Stroop test to measure inhibition (executive function) will be taken pre- and post-exercise. Sensory perception of the drink will be measured immediately post-consumption on Day 5. After a 5-day washout period participants will crossover and begin their second trial.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
Double (Participant, Investigator)

盲法说明

Both isotonic drinks (high nitrate or no nitrate) are deidentified and labelled (coded) by a third party not involved with the research. Randomization and allocation are completed by a third party not involved in the testing.

入排标准

年龄范围
21 Years 至 40 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Age: 21 - 40 years
  • •Healthy and injury-free (e.g., no cardiovascular disease, diabetes mellitus, orthopaedic impairment that interferes with moderate-to-vigorous exercise)
  • •Blood pressure < 130/90 mmHg
  • •Be physically active: Engaging in a minimum of 150 minutes of moderate-intensity exercise or 75 minutes of vigorous-intensity physical activity each week.
  • •Recreational cyclist (Minimum 1 hour cycling per week).
  • •Body mass index: 18.5-25 kg/m2
  • •Non-smoker

排除标准

  • •Any allergies to beetroot or isotonic drink.
  • •Any diagnosed form of cardiometabolic disease (heart disease, stroke, peripheral vascular disease, diabetes, metabolic syndrome, high blood pressure).
  • •Any symptoms contraindicating exercise testing (e.g. chest pains).
  • •Any balance or dizziness problems.
  • •Any chronic medical conditions (whether medicated or not).
  • •Any bone joint problems.
  • •Any Physician diagnosed contraindications to exercise.
  • •Any other health problems that may be a cause for concern or contraindication to exercise.
  • •Any recent Covid vaccination (within last 2 weeks).

研究组 & 干预措施

High nitrate

Experimental

High nitrate isotonic drink

干预措施: Dietary Supplement: High nitrate isotonic drink (Other)

No nitrate

Active Comparator

No nitrate isotonic drink

干预措施: Dietary Supplement: No nitrate isotonic drink (Other)

结局指标

主要结局

Power output during maximal sprint cycling

时间窗: 2 hours after drink ingestion

Peak and mean power output

次要结局

  • Plasma nitrate and nitrite(Pre-drink and 2 hours post-drink)
  • Sensory evaluation (Acceptance and Preference Test Evaluation by Meilgaard et al 2007)(Immediately post-drink (1 minute post-drink))
  • Stroop test(Immediately pre- (2 hours post-drink) and immediately post-exercise (2.5 hours post drink))
  • Salivary nitrate(Pre-drink, 2 hours post-drink and immediately post-exercise (2.5 hours post-drink))
  • Muscle oxygenation(During exercise (2-2.5 hours post drink))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Stephen Burns

Associate Professor

Nanyang Technological University

研究点 (1)

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