Association Between Preoperative Blood Characteristics and Mortality in Abdominal Emergency Surgeries

University of Chile2 sites in 1 country40 target enrollmentOctober 15, 2025

ConditionsSurgical Wound

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Surgical Wound
Sponsor: University of Chile
Enrollment: 40
Locations: 2
Primary Endpoint: Death
Status: Suspended
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

After surgical tissue damage, cellular blood components are involved in tissue repair processes, yet their preoperative characteristics are not considered in routine clinical practice.

Detailed Description

Surgical injuries initiate the recruitment of cellular blood components for tissue repair. Baseline inflammation levels and cellular response to tissue damage are absent from perioperative management algorithms despite their importance in regeneration. This project seeks to examine patients preoperative parameters before surgery and evaluate if there is a correlation with clinical outcomes.

Registry

clinicaltrials.gov

Start Date

October 15, 2025

End Date

December 15, 2027

Last Updated

last year

Study Type

Observational

Sex

All

Investigators

Sponsor

University of Chile

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Patients between 18 and 65 years of age at surgery.
•Patients with acute intra-abdominal pathology requiring emergency surgery.
•A complete blood count was performed in the emergency department of our center within 24 hours before surgery.

Exclusion Criteria

•Patients who are users of anticoagulation before admission for any reason
•Patients who have had previous hospitalization or surgery in the last 6 months.