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Clinical Trials/NCT01550276
NCT01550276
Completed
Not Applicable

Treatment of Tension-type Headache With Articulatory and Suboccipital Soft Tissue Therapy: a Double-blind, Randomized, Placebo-controlled Clinical Trial

University of Valencia1 site in 1 country84 target enrollmentJanuary 2010

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Tension-type Headache
Sponsor
University of Valencia
Enrollment
84
Locations
1
Primary Endpoint
Firstly, an individual clinical interview was conducted to collect socio-demographic data and characteristics of headache in a one-month base period (the previous 4 weeks)
Status
Completed
Last Updated
14 years ago

Overview

Brief Summary

Background. Headache is one of the most common causes of consultation in primary health care and neurology in Europe. Cervical muscle tension can maintain a restriction of joint motion at the suboccipital level, facilitating the referred head pain.

Objective. To evaluate the effectiveness of two manual therapy treatments for tension-type headache.

Methods. A randomized double-blind clinical trial was conducted, for a period of 4 weeks and a follow-up at one month post-treatment. Eighty-four patients with tension-type headache were assigned to 4 groups (3 treatment groups and 1 control group). Treatments included manual therapy of suboccipital soft tissue inhibition, occiput-atlas-axis global manipulation, and a combination of both techniques. Outcome measures were: impact of headache, disability caused by headache, ranges of motion of the craniocervical junction, frequency and intensity of headache, and associated headache symptoms.

Results. After 8 weeks, there were significant improvements in impact of headache (p=0.01), disability (p=0.001), and craniocervical flexion (p=0.03) for the suboccipital soft tissue inhibition group; in headache impact and disability (p=0.000), pain intensity (p=0.02) and craniocervical flexion (p=0.004) and extension (p=0.04) for the occiput-atlas-axis group; and in impact (p=0.002), functional disability (p=0.000), headache frequency (p=0.002) and intensity (p=0.001), craniocervical flexion (p=0.008) and extension (p=0.003) and associated headache symptoms (p=0.01) for the combined therapy group, with effect sizes from medium to large.

Conclusions. Occiput-atlas-axis and combined therapy group treatments are more effective than suboccipital soft tissue inhibition for tension-type headache. The treatment with suboccipital soft tissue inhibition, despite producing less significant results, also has positive effects on different aspects of headache.

Registry
clinicaltrials.gov
Start Date
January 2010
End Date
December 2011
Last Updated
14 years ago
Study Type
Interventional
Study Design
Factorial
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

GEMMA V ESPÍ LÓPEZ, PhD

PhD, PT

University of Valencia

Eligibility Criteria

Inclusion Criteria

  • Age between 18 and 65 years, episodes of headaches lasting from 30 minutes to 7 days, headache having at least two of the following characteristics: \*bilateral location
  • pressing non-pulsating quality
  • mild or moderate intensity
  • not aggravated by routine physical activity.
  • Participants may present photophobia or phonophobia, nausea or vomiting, pericranial tenderness, with evolution of more than three months, and they must be under pharmacological control.

Exclusion Criteria

  • Patients with other types of headache
  • Headache that is aggravated by head movements
  • Metabolic disorders or musculoskeletal complaints previous neck trauma
  • Dizziness
  • Arterial hypertension
  • Advanced degenerative osteoarthritis
  • Neck joint stiffness
  • Signs of malignancy
  • Pregnancy
  • Patients with cardiac devices

Outcomes

Primary Outcomes

Firstly, an individual clinical interview was conducted to collect socio-demographic data and characteristics of headache in a one-month base period (the previous 4 weeks)

Time Frame: up to 4 weeks

This interview gathers information about age, sex, intensity and frequency of headache (with a Visual Analog Scale from 0 to 10), severity of pain (low, moderate, high), qualities of pain (Bilateral location of pain, Pulsating pressure, Not aggravated by physical activity, Photofobia/Phonofobia, Nausea/Vomiting, Pericranial tenderness), cranial location of pain, family history of headache, triggers, aggravating and pain-relieving factors, as well as any previous physiotherapy treatment for headache relief.

Secondary Outcomes

  • Impact of headache on daily life(HIT-6)(up to 8 weeks)
  • Headache Disability Inventory (HDI)(up to 8 weeks)
  • Headache pain intensity(up to 8 weeks)
  • Ranges of motion of the craniocervical junction(up to 8 weeks)
  • Headache diary(up to 8 weeks)

Study Sites (1)

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