ACTRN12618001707257招募中3 期
The Metformin Aneurysm Trial
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 1,954
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •1) An infrarenal AAA with a diameter of 35mm or greater on imaging with the treating doctor indicating that repair is not planned within the next 12 months.
- •2) At least 18 years old and provides valid informed consent
排除标准
- •1) Symptomatic, ruptured or infected AAA;
- •2) Previous abdominal aortic surgery;
- •3) Contraindications to metformin, including renal impairment (eGFR <45ml/min/1.73m2), severe heart failure (defined as New York Heart Association Class IV) requiring in-patient treatment within the last 12 months or leading to shortness of breath at rest, or previous allergic reaction to metformin;
- •4) Current indication for metformin (i.e. diabetes defined by HbA1c 6.5% or greater);
- •5) Involvement in another drug trial;
- •6) Terminal illness
研究者
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