NCT02717767已完成不适用
Measuring Auto-fluorescence of White Corpuscles for the Early Diagnosis and the Monitoring of Pneumonia in Intensive Care Units
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 69
- 试验地点
- 4
- 主要终点
- Pneumonia
研究概览
简要总结
The diagnosis of pneumonia is challenging in Intensive Care Unit. The auto-fluorescence of white corpuscles is altered during pneumonia. In presence of bacterial growth on lung samples, the measure of autofluorescence of white corpuscles could help the clinicians to discriminate bacterial colonization from acute infection.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hospitalization in intensive care units
- •Mechanical ventilation
- •Age > 18 years
- •Collection of a lung sample for bacteriological analysis for the suspicion of a first episode of lung infection.
排除标准
- •Refuse to participate
结局指标
主要结局
Pneumonia
时间窗: 28 days
Diagnosis of pneumonia (Clinical Pulmonary Infection Score \> 6, with assessment of the chest radiography by a blinded investigator)
次要结局
- Clinical Pulmonary Infection Score > 6(day 3)
- Intensive Care unit Length of stay(day 90)
- Mortality(day 90)
- Acute respiratory distress syndrome(day 90)
- Duration of mechanical ventilation(day 90)
研究者
研究点 (4)
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