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Clinical Trials/NCT06149000
NCT06149000
Not yet recruiting
Not Applicable

Migraine Headache Mitigation Utilizing Avulux Color Filtering Lenses

Kaiser Permanente0 sites40 target enrollmentDecember 13, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Migraine
Sponsor
Kaiser Permanente
Enrollment
40
Primary Endpoint
Reduction in migraine frequency
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

This will be a randomized double blind cross over interventional trial to determine if Avulux lenses are able to reduce headache symptoms in patients

Detailed Description

Participants: This study will include a total of 40 participants aged 18 and over who have been screened for migraine headache history. Patients who attended the SBC Headache class with a diagnosis of Migraine from the last 12 months will be selected and assigned a number. Random number set will be used to select the 40 patients. Additional 40 patients will be selected to meet the total initial enrollment of 40 patients in the end. These 40 patients will be randomly assigned to Avulux or Control groups. Each patient will be assigned a unique identifier, and the rest of the correspondents will not use patient demographics. Design: The study will be a randomized, double blind, crossover interventional trial. Participants will be randomly assigned to one of 2 groups of 20. 1. Experimental Group: Participants in this group will wear Avulux lenses during the testing sessions. 2. Control Group: Participants in this group will wear placebo lenses that resemble Avulux lenses but do not have the same optical properties. Procedure: Participants will complete a baseline assessment and self-report migraine frequency using the Redcap migraine diary application. Participants will complete testing sessions with both Avulux and placebo lenses for the duration of 3 months and then switch lenses for the remaining 3 months for comparison and a total study period of 6 months.

Registry
clinicaltrials.gov
Start Date
December 13, 2023
End Date
June 20, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient population: Individuals must have an existing diagnosis code of G43.1 (migraine w aura) or G
  • 10 (migraine w aura, not intractable).
  • Only Kaiser Permanente members receiving care at the Fontana Medical Service Areas will be in consideration.
  • Patients that are \>18
  • There will no restrictions based on biological sex.
  • Participants will be referred to optical by provider (Neurologists/Optometrist/Primary Care physician).
  • Participants must agree to not initiate any new medical management during the trial or be willing to voluntarily withdrawal from participating in the trial

Exclusion Criteria

  • Patients who do not have a migraine diagnosis code in their medical record.
  • Patients that have started a new migraine medication within last 30 days
  • Non-Members of Kaiser Permanente

Outcomes

Primary Outcomes

Reduction in migraine frequency

Time Frame: 6 months

headache days per month documented in a headache diary.

Reduction in migraine severity

Time Frame: 6 months

Severity of headaches on a scale from no, mild, moderate, and sever pain

Secondary Outcomes

  • Improve quality of life(6 months)
  • Medication Use(6 months)

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