application of growth factors after deep cleaning in the type 2 diabetes mellitus patient having gum disease.

Not Applicable

Completed

• Conditions: Health Condition 1: K053- Chronic periodontitisHealth Condition 2: E119- Type 2 diabetes mellitus without complications

• Registration Number: CTRI/2021/06/034280
• Lead Sponsor: Shunmuga Prasanth D

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2022-10-18
• Last Update Posted: 6 February 2023

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 23

Inclusion Criteria

1.Type 2 Diabetes mellitus subjects with the glycaemic status having HbA1c >= 7

2.Subjects on oral medication for the management of Diabetes mellitus.

3.Subject with moderate periodontal disease with the case definition, StageIII and Grade C periodontitis, according to EFP-AAP periodontal disease classification 2017. i.e., Moderate periodontal destruction is defined as sites having >= 5mm probing pocket depth with attachment loss.

4.Moderate periodontal destruction at least, in 2 interproximal sites in each mandibular quadrant.

5.Minimum presence of 4 permanent teeth per mandibular quadrant (excluding 3rd molars).

Exclusion Criteria

1.Sites with pseudo pockets / advanced periodontal destruction with mobility and Grade IV furcation involvement

2.Periodontal therapy within last 6 months

3.Previous history of intake of antibiotics over last 6 months

4.Systemic condition / disease other than Type II DM, having influence on course and treatment outcomes of periodontal disease.

5.Screening for the infectious disease will be done and the subjects with infectious diseases will be excluded.

6.Individuals with known platelet disorders

7.Smokers

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the changes in the: <br/ ><br>Clinical attachment level (CAL) <br/ ><br>before and after therapy within and between the groups.Timepoint: Baseline <br/ ><br>3Months <br/ ><br>6Months

Secondary Outcome Measures

Name	Time	Method
To evaluate the changes in the <br/ ><br> 1.Probing pocket depth (PPD) <br/ ><br>2.Plaque index (PI) <br/ ><br>3.Sulcular Bleeding Index (SBI) <br/ ><br>before and after therapy within and between the groups.Timepoint: Baseline <br/ ><br>3Months <br/ ><br>6Months