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Open-label study on the efficacy of lamotrigine in patients with brain tumor, stroke or head injury, and comorbid depressive symptoms

Not Applicable
Conditions
Depressive symptoms in patients with brain tumor, stroke, or head injuries, and comorbid epilepsy
Registration Number
JPRN-UMIN000009463
Lead Sponsor
Department of Neurosurgery, Shiga University of Medical Science
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
50
Inclusion Criteria

Not provided

Exclusion Criteria

1.abnormal liver function 2.history of allergy to other antiepileptic drugs 3.currently pregnant 4.within two weeks after the patients suffered from head injury or stroke 5.within two weeks after brain surgery 6.the life expectancy is less than six months 7.concent of patients can not be obtained because of disturbance of consciousness or cognitive dysfunction 8.patients demonstrate bad compliance

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Hospital Anxiety and Depression Scale (HADS)
Secondary Outcome Measures
NameTimeMethod
50% responder rate
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