Evaluating the efficacy of probiotic chewable tablets containing lactobacillus reuteri on salivary beta-glucosidase levels in patients with oral malodour as an adjunct to scaling and root planing,a randomized control trial study.
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Salivary beta Glucosidase
研究概览
简要总结
The purpose of the study is to evaluate the efficacy of probiotic chewable tablets containing lactobacillus reuteri on salivary β -glucosidase levels in patients with oral malodour as an adjunct to scaling and root planing –a randomized control trial study. The role of probiotics in reducing the level of salivary β glucosidase and thereby in the treatment of halitosis has been investigated. Previous studies have shown the effect of scaling and root planing (SRP) along with probiotics in halitosis patients. This study is intended for the assessment of probiotic therapy as an adjunct to scaling and root planing and its effect on salivary β glucosidase levels in halitosis patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 19.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Age group 25–60 years 2.Both male and female patients 3.Subjective feeling of bad breath.
- •4.Atleast 16 teeth should be present with a minimum of 4 teeth in each quadrant.
- •5.Systemically healthy individuals.
- •6.Who are willing to participate and have signed written consent.
排除标准
- •1.Presence of any systemic conditions or debilitating diseases.
- •2.Smokers, alcoholics, pregnant or lactating women.
- •3.A recent history or presence of any acute or chronic infections.
- •4.Patients who had undergone periodontal therapy in the last 6 months.
- •5.Patients who are paan/tobacco/betel nut users.
- •6.Patients who are physically or mentally challenged.
- •7.Patients with periodontal disease or rampant decay with excessive open carious lesions.
- •8.Patients with Xerostomia.
结局指标
主要结局
Salivary beta Glucosidase
时间窗: At Baseline,1 Month and 3 Months
次要结局
- salivary beta glucosidase level decreased in probiotic supplementation.(3 months)
研究者
LAKSHMI C
Educare Institute Of Dental Sciences