Sentinel surveillance of imported dengue in returning travelers - trends and virus evolutio
Completed
- Conditions
- denguedengue fever10047438
- Registration Number
- NL-OMON35589
- Lead Sponsor
- meå University, Dept. Public Health and Clinical Medicine, Epidemiology and Global Health
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
Travelers (all age groups) returning from dengue endemic regions who present with an acute febrile illness suspicious of dengue (onset of fever <=5 days*) within the possible incubation period of a dengue infection (<=21 days).
Exclusion Criteria
Travelers presenting with concomitant co-infections (e.g. malaria, rickettsial infections, etc.)
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Only cases with laboratory confirmed dengue infection will be included in the<br /><br>final data analysis.<br /><br><br /><br>number of patients with dengue fever returning from a specific area<br /><br>number of patients with severe dengue fever according to the revised WHO dengue<br /><br>case classification and classical case definition<br /><br>percentage of sequence similarities and differences of dengue virus isolates</p><br>
- Secondary Outcome Measures
Name Time Method <p>identification of viral genetic factors associated with severe clinical<br /><br>manifestions</p><br>