Impact of Augmented Sensory Feedback on Motor Control and Risk of Falling in Cancer-Related Neuropathic Patients"
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 40
- Locations
- 2
- Primary Endpoint
- improvement of balance which was assessed by fall risk scale
Study Overview
Brief Summary
this research studied the effect of augmented sensory feedback program on motor control and risk of falling in patient with CIPN.
Detailed Description
Design: A randomized control trial was conducted to investigate the impact of augmented sensory feedback paradigm on motor control and risk of falling in patient with Chemotherapy-induced peripheral neuropathy. Data were collected pre and post treatment from out-patient clinic of the Faculty of Medicine and Faculty of Physical Therapy South Valley University, between January 2023and March 2024. The study was approved by the ethical committee of the Faculty of Physical Therapy, South Vally University, Egypt. The study protocol was explained in detail to every patient and signed written consent was obtained before participation.
Participants: forty female patients with CIPN were recruited from out-patient clinic of the Faculty of Medicine and Faculty of Physical Therapy South Valley University, between January 2023and March 2024.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Triple (Participant, Care Provider, Outcomes Assessor)
Eligibility Criteria
- Ages
- 35 Years to 60 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Forty female with age from 35-60 years
- •clinically diagnosed with CIPN after recovery from stage I or II breast cancer
- •The strength at the toes, ankles, knees, and hips, as determined by manual muscle tests, of at least 3/
- •The patients can walk independently with or without any assistive devices.
Exclusion Criteria
- •Patients with a history of hereditary peripheral neuropathy
- •Diseases that may contribute to peripheral nerve damage, such as diabetes or renal insufficiency, alcohol abuse, HIV, and vasculitis.
- •Patient who had central or peripheral neurologic disease, brain or spinal cord metastases
- •Orthopedic problems influencing gait, or foot ulcer at the moment of intake.
- •Patients with vestibular or neurological problems influencing gait parameters
- •Subjects who had participated in regular exercise, as defined as 150 min of light-to-moderate intensity exercise per week over the past year, were excluded from this trial.
Arms & Interventions
control group 20 Patients"
Cancer-Related Neuropathic Patients"
Intervention: selected physical therapy program as arm excercises (Combination Product)
study group 20 Patients"
Cancer-Related Neuropathic Patients"
Intervention: Gradual Intermittent pneumatic compression therapy (IPC),Balance excercises.PNF technique (Combination Product)
Outcomes
Primary Outcomes
improvement of balance which was assessed by fall risk scale
Time Frame: one and half month
improvement in feet sensitivity and motor control and risk of falling in both groups in favor of the study group.
Stability measures
Time Frame: one and half month
postural stability was measured using a Biodex Balance System SD (950-440 with version 4.X software)
Sensory feedback
Time Frame: one and half month
Sensory feedback was assessed by using Semmes-Weinstein monofilament (SWM)
Secondary Outcomes
No secondary outcomes reported
Investigators
Abeer Abdrabo
Lecture of physical Therapy, Department of Neuromuscular Disorder, Faculty for Physical Therapy, Cairo University, Cairo, Egypt
Isra University, Jordan