NL-OMON41523已完成不适用
Withdrawal of antiepileptic drugs in low grade and anaplastic glioma patients after long-term seizure freedom - Withdrawal of AEDs in glioma patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 75
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •(1) adults (>18 years)
- •(2) histologically confirmed LGG or anaplastic glioma (WHO grade I pilocytic astrocytoma, pleomorphic xanthoastrocytoma, subependymal giant cell astrocytoma, and subependymoma; WHO grade II astrocytoma , mixed oligo-astrocytoma, oligodendroglioma; ependymoma; WHO grade III brain tumours (anaplastic astrocytoma, anaplastic oligodendroglioma, anaplastic oligo-astrocytoma or anaplastic ependymoma))
- •(3) presence of epilepsy and treatment with AEDs
- •(4) past anti-tumour treatment (surgical resection, brain irradiation or temozolomide chemotherapy)
- •(5) stable disease with absence of clinical or radiological signs of tumour recurrence during the past year
- •(6) seizure freedom for at least 1 year counted from the date of first surgery, last day of first irradiation or last day of first temozolomide chemotherapy cycle; OR seizure freedom for at least 2 years from the last non-acute symptomatic post-therapy seizure.
排除标准
- •Patients who underwent biopsy only.
研究者
相似试验
进行中（未招募）
1 期
Rapid versus slow withdrawal of antiepileptci monotherapy in two-year seizure free patients.EpilepsyEUCTR2015-004827-30-ITAZIENDA OSPEDALIERA BIANCHI-MELACRINO-MORELLI350
招募中
不适用
Reducing antiepileptic medication during a multiple-day video-EEG to investigate the feasibility of epilepsy surgery: what is the best way (safest and most efficious) to reduce antiepileptic drugs?Epilepsy, epilepsy surgeryNL-OMON22478niverstiy Medical Center Utrecht850
已完成
不适用
Reduction of concomitant antiepileptic medication after successful treatment with levetiracetam; a randomised open label study comparing delayed withdrawal to slow withdrawal.EpilepsyISRCTN72533351Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)
招募中
3 期
Withdrawing off-label antipsychotics in people with intellectual disabilities: why does it fail?NL-OMON55806Erasmus MC, Universitair Medisch Centrum Rotterdam122
进行中（未招募）
1 期
Withdrawing off-label antipsychotics in people with intellectual disabilities: why does it fail?People with challenging behavior and off-label antipsychotic useEUCTR2016-002859-19-NLErasmus MC