A clinical trial to establish the proper diagnosis and therapy of Hypereosinophilic syndrome.
Not Applicable
- Conditions
- Hypereosinophilic syndrome, chronic eosinophilic leukemia
- Registration Number
- JPRN-UMIN000008653
- Lead Sponsor
- Kobe University Medical School Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
1) Presence of any other active neoplasm 2) Prior anti-leukemic treatment within two weeks. 3) Psychological disorder 4) Hypersensitivity to ingredient of Imatinib 5) Pregnant or nursing women 3) Whom the investigator considered inappropriate to this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Imatinib responsiveness; complete remission(CR) ratio, time to achievement, time to progression.
- Secondary Outcome Measures
Name Time Method 1)Organic dysfunction caused by hepereosinophilia 2)Expression levels and stractual changes of F-P fusion mRNA, and mutational analysis in imatinib resistance 3)Adverse effects of Imatinib