jRCT2031210139暂停不适用
ONO-7913-02: Multi-center, open-label phase 1 study of ONO-7913 (magrolimab) in combination with azacitidine in patients with MDS
试验速览
- 阶段
- 不适用
- 状态
- 暂停
- 入组人数
- 12
- 主要终点
- -
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Single Arm Study
- 干预模型
- Single Assignment
- 主要目的
- Treatment Purpose
- 盲法
- Open(masking Not Used)
入排标准
- 年龄范围
- 20age old over 至 No limit（—）
- 性别
- All
入选标准
- •Patients with histological confirmation of MDS defined according to WHO classification, with an IPSS-R risk category of intermediate, high, or very high risk
- •Patients judged by the investigator or subinvestigator to be appropriate for treatment with azacitidine
- •Patients with ECOG Performance Status of 0 to 1
排除标准
- •Patients who are determined to undergo allogeneic hematopoietic stem cell transplantation
- •Patients previously treated with azacitidine
- •Patients with severe complication
结局指标
主要结局
-
Tolerability, safety
次要结局
未报告次要终点
研究者
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