Prevalence of Alloantibodies in Transfusion dependent Thalassemia patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- To study the frequency of alloimmunization in patients diagnosed with thalassemia dependent on regular blood transfusions.
研究概览
简要总结
The present study is a retrospective study where secondary data obtained from previous laboratory records of patients diagnosed with thalassemia, receiving regular blood transfusions at Lok Nayak Hospital during the study period from 1 November 2023- 31 January 2024 will be analysed. The patients had been admitted for receiving blood transfusion. Blood samples had been collected immediately prior to the transfusion. These samples had been subjected to antibody screening. Plasma samples had been screened for alloantibodies by the indirect antiglobulin test utilizing commercial three cell panel, Diacell I+II+III. Plasma samples that had exhibited a positive result with ID-Diacell antibody screen underwent antibody identification utilizing an extended commercial 11-cell identification panel.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 1.00 Day(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients diagnosed with thalassemia dependent on regular blood transfusion.
排除标准
- •Patients diagnosed with thalassemia not dependent on regular blood transfusion.
结局指标
主要结局
To study the frequency of alloimmunization in patients diagnosed with thalassemia dependent on regular blood transfusions.
时间窗: At baseline
次要结局
- To correlate the frequency of alloimmunization in transfusion dependent thalassemia patients with the red blood cell requirement(At baseline)
研究者
Sunil Kumar
Lok Nayak Hospital