Exploratory Investigation of the Inhibitory Effect of Codium fragile Extract Lectin on Biofilm Formation on Human Tooth Surface
Phase 1
- Conditions
- Oral Biofilm Infection
- Registration Number
- JPRN-UMIN000053076
- Lead Sponsor
- Okayama University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 15
Inclusion Criteria
Not provided
Exclusion Criteria
Allergic to any of the tested materials (if allergic symptoms occur) Pregnant or lactating mothers Other subjects who are judged to be ineligible by the investigator based on their schedule or dental disease status.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in the amount of bacteria on the tooth surface (calculated as ATP amount/area) after 6 hours
- Secondary Outcome Measures
Name Time Method Changes in oral flora Changes in cariogenic bacteria count, acidity, buffer capacity, leukocyte count, protein, and ammonia in saliva Presence or absence of abnormal findings in the oral mucosa