Development and Evaluation of Smartphone App for Initiation of Protective Ventilation. Clinical Impact of Instrumental Dead Space Reduction on Physiologic Parameter Based on the Smartphone App

Laval University1 site in 1 country20 target enrollmentNovember 1, 2019

ConditionsARDS, Human Mechanical Ventilation Complication Humidifier Lung

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: ARDS, Human
Sponsor: Laval University
Enrollment: 20
Locations: 1
Primary Endpoint: PaCO2 Variation
Status: Recruiting
Last Updated: 3 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Clinical evaluation of a new educative tools (Smartphone application) based on impact of instrumental dead space reduction after initiation of protective ventilation during mechanical ventilation.

Registry

clinicaltrials.gov

Start Date

November 1, 2019

End Date

June 30, 2024

Last Updated

3 years ago

Study Type

Interventional

Study Design

Crossover

Sex

All

Investigators

Sponsor

Laval University

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Age \> 18 years old
•Mechanical ventilation (control,assist control or SIMV mode)
•haemodynamic stability (vasopressor \< 0.2 ug/kg/min)
•no prone position schedule in the next 2 hours following procedure inclusion
•presence of an Arterial catheter

Exclusion Criteria

•ECMO or anticipate ECMO
•body temperature \< 36.0 for post operative patient (cardiac surgery)

Outcomes

Primary Outcomes

PaCO2 Variation

Time Frame: 120 minutes post intervention

The primary outcome is to evaluate the PaCO2 variation at the end of condition 2 (after 30 minutes with protective ventilation+ HME) and condition 4 (30 minutes after Tidal volume reduction + Heater humidifier). Variation \<= 10% of PaCO2

Secondary Outcomes

Correlation between PCO2 variation and alveolar ventilation variation(60 and 90 minutes post intervention)
Hemodynamic impact vs pH(Baseline, 30, 60, 90 and 120 minutes post intervention)