The Comparison of Treatment Sequence of Parallel rTMS and Rehabilitation and Rehabilitation Only

Not Applicable

Completed

• Conditions: post-stroke hemiparesis

• Registration Number: JPRN-jRCT1091220215
• Lead Sponsor: The Jikei University School of Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-06-12
• Study Completion: 2020-03-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 47

Inclusion Criteria

1) motor-dominant aphasia caused by left hemispheric stroke in a right-handed subject; 2) age at intervention between 20-80 years; 3) time between the onset of stroke and treatment of more than 12 months; 4) history of a single stroke only (no bilateral cerebrovascular lesion); 5) no cognitive impairment with a pretreatment Mini Mental State Examination score of more than 26; 6) clinical confirmation of a plateau state (no increases in the WAB and Token Test scores as measured by a speech therapist from the institution in the last 3 months); 7) no active physical or mental illness requiring medical management; 8) no contraindications to atomoxetine administration (serious cardiovascular disturbance, pheochromocytoma, closed angle glaucoma and impaired liver function); and 9) sufficient understanding of the study contents.

Exclusion Criteria

contraindications to atomoxetine administration (serious cardiovascular disturbance, pheochromocytoma, closed angle glaucoma and impaired liver function)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
safety, feasibility, and efficacy

Secondary Outcome Measures

Name	Time	Method
Japanese version of WAB and the Token Test