Periodontal Impact of Eating Disorders (the PERIOED Study)

• Conditions: Periodontal Diseases; Bulimia Nervosa; Eating Disorder; Anorexia Nervosa
• Interventions: Other: diagnostic

• Registration Number: NCT02960152
• Lead Sponsor: University Paris 7 - Denis Diderot

Brief Summary

This study evaluated the periodontal status of patients suffering from eating disorders (anorexia nervosa and bulimia nervosa). The work hypothesis is that eating disorder patients have a higher risk for periodontal diseases than non-eating disorder subjects.

Detailed Description

Eating disorders have been associated with poor oral health. However, the relationship between eating disorders and periodontal diseases is less-established. Participants will be periodontally assessed using a full-mouth clinical evaluation.

Study Timeline

• Study Start: 2014-10
• Study First Submitted: 2016-11-07
• Study First Submitted QC: 2016-11-08
• Study First Posted: 2016-11-09
• Status Verified: 2017-05
• Last Update Submitted: 2017-05-01
• Last Update Posted: 2017-05-02
• Primary Completion: 2017-09
• Study Completion: 2018-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 90

Inclusion Criteria

• In and out eating disorder patients
• Subject with a diagnosis of anorexia nervosa or bulimia nervosa for at least 5 years
• Subject affiliated to the French social insurance

Exclusion Criteria

• Subject who do not speak French
• Subject who is not able to read and/or understand the information form
• Subject who take anti-inflammatory medications or antibiotics at dental examination
• Subject who has received any dental treatment that could interfere with the periodontal status 3 month before the clinical examination (scaling and root planning, orthodontic treatment ongoing)
• Subject who has less than 10 teeth

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Anorexia Nervosa	diagnostic	interview and periodontal full-mouth examination
Bulimia Nervosa	diagnostic	interview and periodontal full-mouth examination
Control	diagnostic	interview and periodontal full-mouth examination

Primary Outcome Measures

Name	Time	Method
Clinical Attachment Loss (CAL)	at examination day	Periodontal probing depth and gingival recession are measured in millimeters using a manual periodontal probe (HuFriedy PCP UNC 15 probe, Chicago, IL, USA). At the clinical examination day, CAL is calculated as periodontal probing depth (mm) + gingival recession (mm) at 6 sites per tooth.

Secondary Outcome Measures

Name	Time	Method
gingival inflammation	at examination day	Gingival inflammation is measured by bleeding on probing score (%) at 6 sites per tooth.

Trial Locations

Locations (2)

Rothschild Hospital; 🇫🇷 Paris, France

Paul Brousse Hospital; 🇫🇷 Villejuif, France