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Visualization of occult endoleaks after endovascular aortic aneurysm repair (EVAR) using Vasovist - a pilot study

Completed
Conditions
aneurysm
10002363
Registration Number
NL-OMON29761
Lead Sponsor
niversitair Medisch Centrum Utrecht
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

minmally 1 years after EVAR
in whom CTA demonstrated no decrease in outer diameter of the aneurysm
in whom no endoleak was detected on CTA
MR must be completed within 1 month after the CT examination.

Exclusion Criteria

contraindications for MRI-examination
contraindication for use of contrast agent

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Number of occult endoleaks only detected at late MR after positional change of<br /><br>the patients<br /><br>Endoleaks will be graded on a 5-point scale (no endoleak, possibly endoleak,<br /><br>probably endoleak, definitely endoleak, not diagnostic).</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Number of occult endoleaks detected by<br /><br>- delayed CT<br /><br>- dynamic MRA<br /><br>- dynamic MRA + MRA delay 1<br /><br>- MRA delay 2<br /><br>- T1-w postcontrast spin echo images (delay 1)<br /><br>- T1-w postcontrast spin echo images (delay 2)<br /><br>• Number of endoleaks detected by<br /><br>- static MRA (first-pass)<br /><br>- MRA delay 1<br /><br>- MRA delay 2<br /><br>• Thrombus enhancement<br /><br>• Change in reader confidence for the detection of endoleaks</p><br>
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