ACTRN12624001137583进行中（未招募）4 期
Effect Of Testosterone Replacement On Anemia And Quality Of Life Amongst Patients On Maintenance Hemodialysis
Dr Qurat Ul Ain Azam - Pak Emirates Military Hospital0 个研究点目标入组 24 人开始时间: 2024年9月20日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 24
- 主要终点
- any change in hemoglobin levels[Haemoglobin levels by running blood samples in automated hematology cbc analysers Baseline and at every months upto 6 months following the intervention]
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 80 Years（—）
- 性别
- Male
入选标准
- •Patients diagnosed with end-stage renal disease (ESRD) requiring maintenance hemodialysis.
- •Patients with documented anemia, defined as haemoglobin levels < 10 g/dL
- •Patients with stable medical conditions, defined as absence of acute illness or major surgical procedures within the past three months.
- •Patients who have been on a stable hemodialysis regimen for at least three months prior to enrollment.
排除标准
- •Patients with known hypersensitivity or contraindications to testosterone replacement therapy (TRT).
- •Patients with active malignancy, including prostate cancer.
- •Patients with uncontrolled hypertension (systolic blood pressure > 180 mmHg or diastolic blood pressure > 110 mmHg).
- •Patients with severe liver disease (e.g., cirrhosis) or severe hepatic dysfunction (e.g., Child-Pugh class B or C).
- •Patients with severe cardiac disease (e.g., congestive heart failure, recent myocardial infarction) or unstable cardiovascular conditions.
- •Patients with a history of thromboembolic events (e.g., deep vein thrombosis, pulmonary embolism).
- •Patients with significant psychiatric illness or cognitive impairment that may affect their ability to participate in the study or provide informed consent.
结局指标
主要结局
any change in hemoglobin levels[Haemoglobin levels by running blood samples in automated hematology cbc analysers Baseline and at every months upto 6 months following the intervention]
次要结局
- Quality of life[Questionnaire base quality of life assessment utilizing WHOQOL-BREF Baseline and at every month till 6 months following intervention]
研究者
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