The effectiveness of mindfulness based cognitive therapy (MBCT) in adults with chronic, therapy resistant depression in a mental healthcare setting?
Completed
- Conditions
- chronic depressionmajor depressive disorder (chronic)10027946
- Registration Number
- NL-OMON37200
- Lead Sponsor
- Pro Persona (lokaties Nijmegen, Arnhem, Ede en Tiel)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Patients with a major depressive disorder (according to DSM-IV) with a duration of one year or longer. Patients have responded insufficiently (IDS >21, moderate depression) to a therapeutic dose of antidepressant medication and a psychotherapy protocol (cognitive behavioral therapy or interpersonal psychotherapy).
Exclusion Criteria
Bipolar disorder
Any primary psychotic disorder
Clinically relevant neurological or other somatic illness
Current alcohol or drug misuse
Use of high dosage of benzodiazepines (>2 mg lorazepam equivalents daily)
Recent Electro Convulsive Therapy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary outcome measure will consist of a reduction in depressive symptoms<br /><br>according to the Inventory of Depression symptomatology (IDS-SR, Rush, Gullion,<br /><br>Base et al, 1996).</p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary outcomes will include: rumination (Ruminative Response Scale and<br /><br>Rumination on Sadness Scale (Raes et al, 2003), mindfulness skills (Five Facet<br /><br>Mindfulness Questionnaire, Baer et al, 2006), self-compassion (Self Compassion<br /><br>Scale; Neff, 2003) and quality of life (QOL WHO, World health Organization,<br /><br>2004) and general health (EQ-5D; Dolan et al, 1997).</p><br>