Acupuncture Manipulation of Fanzhen jieci for Discogenic Sciatica: A Randomized Controlled Clinical Trial
- Conditions
- Discogenic Sciatica
- Registration Number
- ITMCTR1900002382
- Lead Sponsor
- Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. Unilateral leg pain diagnosed as discogenic sciatica and leg pains that correlate with CT or MRI findings of lumbar disc herniation;
2. Sciatica patients with an average leg pain VAS of 40 mm or higher in the last 24 hours;
3. Aged 18 to 75 years;
4. Patients who agree to follow the trial protocol.
1. Severe cases with central or giant or ruptured lumbar disc herniation, cauda equina syndrome, foot drop, or surgery requirements;
2. Progressive neurological symptoms after 3 months of strict conservative treatment (e.g., nerve root adhesion, crossed straight-leg testing, or obvious muscle atrophy);
3. Severe cardiovascular, liver, kidney, hematopoietic system diseases, autoimmune diseases, or poor nutritional status;
4. Subjects with cognitive impairment;
5. Subjects who received acupuncture for sciatica within the past month.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method change from baseline in mean weekly VAS of leg pain;
- Secondary Outcome Measures
Name Time Method Serum mitochondrial DNA concentration;Oswestry disability index;Short Form 36-item Health Survey(SF-36);Change in mean weekly VAS of low back pain;Brief Pain Inventory;